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Dr. Camacho is a computational biophysicist, with expertise in the areas of protein folding, binding, regulation, and drug discovery. He is particularly interested in understanding the role of flexibility and intrinsically disordered protein regions in regulatory functions. Past accomplishments include revealing the role of desolvation in protein specificity; describing the role of anchor residues as key determinant of molecular recognition; and, developing the first automated method to predict docked proteins “ClusPro”. More recently, the Lab of Dr. Camacho has revolutionize rational drug discovery by developing the first interactive technologies for virtual screening, including the development of novel libraries specially designed to disrupt protein-protein interactions.